Simone Spuler: Die Muskelretterin. Neue Therapien mit der Genschere CRISPR

We take our muscles for granted in our daily lives. But the mechanism of muscle loss due to genetic or age-related diseases is still unclear and there are no therapies. Simone Spuler and her team are using stem cells and the CRISPR gene scissors to prevent people with genetic diseases from losing their muscle tissue - or even to repair it. Spuler combines her work in the clinic, laboratory and start-up to make the first therapeutic approaches possible for diseases that were previously considered incurable.

Prof. Dr. Simone Spuler is an expert in hereditary muscle diseases at the Experimental and Clinical Research Center (ECRC), a joint institution of Charité - Universitätsmedizin Berlin and the Max Delbrück Center. She has conducted research at renowned institutes in Germany and the USA. In 2023, she received the UNIPRENEURS award from the German Federal Ministry of Education and Research for founding the start-up for regenerative therapies MyoPax GmbH.